College Football 2023: Week 6 Predictions for Every Game

David KenyonFeatured Columnist IVOctober 5, 2023

College Football 2023: Week 6 Predictions for Every Game

0 of 7

    Quinn Ewers
    Quinn EwersWilliam Purnell/Icon Sportswire via Getty Images

    What the Week 6 schedule in college football lacks in volume is atoned for through a variety of key matchups.

    As many programs enter an idle weekend, we're set to watch Oklahoma and Texas in the rivalry's final Big 12 showdown. Maryland and Ohio State square off in a battle of unbeatens. Three contests—LSU at Missouri, Alabama at Texas A&M and Kentucky at Georgia—headline the SEC slate, and Notre Dame travels to Louisville, too.

    At least three unbeaten teams will take their first loss of the season, and several others may follow suit.

    We've also reached a lovable landmark: Early midweek games!

    By the time you're reading this, no less than two matchups have been completed. Thanks for keeping us entertained on Wednesday night, Conference USA. Also, see you soon, MACtion!

    The rankings are based on the latest AP Top 25.

AP Nos. 25-21

1 of 7

    LSU QB Jayden Daniels
    LSU QB Jayden DanielsKevin Langley/Icon Sportswire via Getty Images

    No. 10 Notre Dame (5-1) at No. 25 Louisville (5-0), 7:30 p.m. ET

    See No. 10 Notre Dame for prediction.


    No. 24 Fresno State (5-0) at Wyoming (4-1), 8 p.m. ET

    The well-earned optimism around Fresno State is set for a fierce challenge in the altitude of Laramie. Earlier this season, Wyoming took down Texas Tech. Fresno State's defense has thrived so far and should be the difference on Saturday night. But this isn't a comfortable matchup for the undefeated Bulldogs.

    Prediction: Fresno State 24, Wyoming 20


    No. 23 LSU (3-2) at No. 21 Missouri (5-0), Noon ET

    See No. 21 Missouri for prediction.


    No. 22 Tennessee (4-1), Idle


    No. 23 LSU (3-2) at No. 21 Missouri (5-0), Noon ET

    After watching Ole Miss run around LSU all night, I wouldn't be confident that the defense can stop an efficient Missouri attack, either. Still, I'm inclined to trust the powerful LSU offense will propel the favored Bayou Bengals to a tough, high-scoring road win.

    Prediction: LSU 41, Missouri 34

AP Nos 20-16

2 of 7

    Miami WR Colbie Young
    Miami WR Colbie YoungPeter Joneleit/Icon Sportswire via Getty Images

    No. 20 Kentucky (5-0) at No. 1 Georgia (5-0), 7 p.m. ET

    See No. 1 Georgia for prediction.


    No. 19 Duke (4-1), Idle


    No. 18 Utah (4-1), Idle


    Georgia Tech (2-3) at No. 17 Miami (4-0), 8 p.m. ET

    Georgia Tech has quietly averaged 6.8 yards per snap behind Texas A&M transfer Haynes King. However, the Yellow Jackets' poor run defense—the worst in the Power Five—is a major concern opposite a Miami offense that ranks third nationally in yards per carry. The return of star safety Kam Kinchens provides a boost to Miami's defense, too.

    Prediction: Miami 38, Georgia Tech 27


    Arkansas (2-3) at No. 16 Ole Miss (4-1), 7:30 p.m. ET

    Here's a prototypical hangover game, right? Ole Miss just racked up 55 points and 700-plus yards against LSU. Arkansas enters the contest on a three-game skid. Ole Miss is the better team, has home-field advantage and should win. But it might be a little nerve-wracking at times, too.

    Prediction: Ole Miss 37, Arkansas 31

AP Nos. 15-11

3 of 7

    UNC QB Drake Maye
    UNC QB Drake MayeG Fiume/Getty Images

    No. 15 Oregon State (4-1) at California (3-2), 10 p.m. ET

    Will the defense travel? As long as that happens, Oregon State should navigate its trip to Berkeley unscathed. However, Cal is an opportunistic squad that leads all Power Five programs with 13 takeaways. That's the obvious way to flip the script and spring an upset.

    Prediction: Oregon State 27, Cal 20


    Syracuse (4-1) at No. 14 North Carolina (4-0), 3:30 p.m. ET

    After a favorable four-game stretch to open the season, Syracuse hit a wall opposite Clemson. The offense mustered only 281 yards in a 31-14 loss at home. Now, the Orange travel to face a balanced—though not overwhelming—UNC roster. North Carolina probably won't run away, but the outcome likely won't be in immense doubt, either.

    Prediction: North Carolina 34, Syracuse 23


    No. 13 Washington State (4-0) at UCLA (3-1), 3 p.m. ET

    This is one of those "I'd love to be wrong" moments. From a narrative view, Washington State is such an awesome story. The outcasts of conference realignment are 4-0 and shaking up an imploding Pac-12. But a trip to UCLA and its disruptive, productive defense could become a big problem for a Wazzu offense that leans heavily on the passing game.

    Prediction: UCLA 29, Washington State 24


    No. 12 Oklahoma (5-0) vs. No. 3 Texas (5-0), Noon ET

    See No. 3 Texas for prediction.


    No. 11 Alabama (4-1) at Texas A&M (4-1), 3:30 p.m. ET

    Both programs lost in Week 2 but have responded—even if not always impressively—with three straight wins. Since those setbacks were of the nonconference variety, this is a crucial SEC game. One major challenge for Bama is that the offense seems to lack go-to receivers, while A&M has Evan Stewart and Ainias Smith. That may be the difference in what should be a low-scoring clash in College Station.

    Prediction: Texas A&M 23, Alabama 20

AP Nos. 10-6

4 of 7

    USC QB Caleb Williams
    USC QB Caleb WilliamsJordon Kelly/Icon Sportswire via Getty Images

    No. 10 Notre Dame (5-1) at No. 25 Louisville (5-0), 7:30 p.m. ET

    Louisville quarterback Jack Plummer has notched 10.7 yards per attempt in five wins, so the explosiveness of the Cardinals' offense must be respected. However, he's also tossed six interceptions—with at least one in four games. That's a problematic trend opposite Notre Dame, which has only two giveaways all season.

    Prediction: Notre Dame 31, Louisville 24


    Arizona (3-2) at No. 9 USC (5-0), 10:30 p.m. ET

    Two weeks ago, Arizona State put a scare into USC. Last Saturday, Arizona nearly shocked Washington. It's safe to say USC should know better than to overlook the Wildcats. Nevertheless, it's unlikely that Arizona—which is 106th nationally in yards allowed per pass attempt—will find a way to contain Caleb Williams and the USC passing game.

    Prediction: USC 41, Arizona 27


    No. 8 Oregon (5-0), Idle


    No. 7 Washington (5-0), Idle


    No. 6 Penn State (5-0), Idle

AP Nos. 5-1

5 of 7

    Michigan RB Blake Corum
    Michigan RB Blake CorumBob Kupbens/Icon Sportswire via Getty Images

    Virginia Tech (2-3) at Florida State (4-0), 3:30 p.m. ET

    Quick golf clap for Virginia Tech, which snapped a three-game losing streak with a 38-21 win over Pitt. But the Hokies are a hefty underdog for a trip to Florida State, which had an extra week to prepare and likely has too much firepower on offense for VT to match.

    Prediction: Florida State 38, Virginia Tech 17


    Maryland (5-0) at No. 4 Ohio State (4-0), Noon ET

    While most Big Ten attention is focused on Michigan, OSU and Penn State, what a fun twist it would be for Maryland to officially crash the party. Ohio State struggled to put away the Terps last season, too. Between home-field advantage, an improved defense and the overall talent differential in the Buckeyes' favor, though, an upset looks just out of reach for Maryland.

    Prediction: Ohio State 30, Maryland 24


    No. 12 Oklahoma (5-0) vs. No. 3 Texas (5-0), Noon ET

    Both defenses put together a spectacular opening month, but their performances will be tested in a massive way inside the Cotton Bowl. Oklahoma and Texas are each averaging 6.9 yards per snap. In such a tight matchup, red-zone efficiency is often a decisive factor. It's therefore concerning that Texas has a 52.4 percent touchdown rate (108th nationally) inside the 20-yard line.

    Prediction: Oklahoma 31, Texas 27


    No. 2 Michigan (5-0) at Minnesota (3-2), 7:30 p.m. ET

    Michigan has surrendered no more than seven points in each of its five victories this season. I'm not sensing much danger from a Minnesota offense that is 98th in yards per snap and 103rd in yards per game.

    Prediction: Michigan 38, Minnesota 7


    No. 20 Kentucky (5-0) at No. 1 Georgia (5-0), 7 p.m. ET

    Over the last four seasons, Kentucky has limited UGA to 21 points or less in three matchups. Conversely, the 'Cats haven't surpassed 17 points against the Dawgs since 2016. Kentucky's key strength is running back Ray Davis, and Georgia just yielded 219 rushing yards to Auburn. But that total is less worrying when you consider two Auburn quarterbacks tallied 125 of those yards, and UK's Devin Leary is not a mobile threat.

    Prediction: Georgia 24, Kentucky 10

Rest of the Slate, Part I

6 of 7

    Wisconsin RB Braelon Allen
    Wisconsin RB Braelon AllenZach Bolinger/Icon Sportswire via Getty Images

    Sam Houston (0-4) at Liberty (4-0), Thursday, 7 p.m. ET
    Prediction: Liberty 27, Sam Houston 14

    Western Kentucky (3-2) at Louisiana Tech (3-3), Thursday, 8 p.m. ET
    Prediction: WKU 34, Louisiana Tech 30

    Kansas State (3-1) at Oklahoma State (2-2), Friday, 7:30 p.m. ET
    Prediction: Kansas State 33, Oklahoma State 20

    Nebraska (2-3) at Illinois (2-3), Friday, 8 p.m. ET
    Prediction: Illinois 27, Nebraska 17

    Rutgers (4-1) at Wisconsin (3-1), Noon ET
    Prediction: Wisconsin 27, Rutgers 16

    Western Michigan (2-3) at Mississippi State (2-3), Noon ET
    Prediction: Mississippi State 41, WMU 14

    Boston College (2-3) at Army (2-2), Noon ET
    Prediction: Army 24, Boston College 20

    William & Mary (4-1) at Virginia (0-5), Noon ET
    Prediction: Virginia 23, William & Mary 19

    Toledo (4-1) at Massachusetts (1-5), Noon ET
    Prediction: Toledo 38, UMass 24

    Marshall (4-0) at North Carolina State (3-2), 2 p.m. ET
    Prediction: NC State 24, Marshall 16

    UTSA (1-3) at Temple (2-3), 2 p.m. ET
    Prediction: UTSA 30, Temple 24

    Central Michigan (3-2) at Buffalo (1-4), 2 p.m. ET
    Prediction: Central Michigan 22, Buffalo 17

    Howard (2-2) at Northwestern (2-3), 3 p.m. ET
    Prediction: Northwestern 37, Howard 14

    North Texas (2-2) at Navy (1-3), 3:30 p.m. ET
    Prediction: North Texas 28, Navy 21

    Texas State (4-1) at Louisiana (3-2), 3:30 p.m. ET
    Prediction: Texas State 34, Louisiana 31

Rest of the Slate, Part II

7 of 7

    TCU QB Chandler Morris
    TCU QB Chandler MorrisRon Jenkins/Getty Images

    Wake Forest (3-1) at Clemson (3-2), 3:30 p.m. ET
    Prediction: Clemson 35, Wake Forest 24

    Purdue (2-3) at Iowa (4-1), 3:30 p.m. ET
    Prediction: Iowa 17, Purdue 13

    Ball State (1-4) at Eastern Michigan (2-3), 3:30 p.m. ET
    Prediction: Eastern Michigan 31, Ball State 20

    Bowling Green (2-3) at Miami (Ohio) (4-1), 3:30 p.m. ET
    Prediction: Miami 27, Bowling Green 17

    Northern Illinois (1-4) at Akron (1-4), 3:30 p.m. ET
    Prediction: NIU 23, Akron 20

    Kent State (1-4) at Ohio (4-1), 3:30 p.m. ET
    Prediction: Ohio 34, Kent State 14

    Central Florida (3-2) at Kansas (4-1), 4 p.m. ET
    Prediction: Kansas 36, UCF 31

    Vanderbilt (2-4) at Florida (3-2), 4 p.m. ET
    Prediction: Florida 31, Vanderbilt 17

    South Florida (3-2) at UAB (1-4), 4 p.m. ET
    Prediction: USF 33, UAB 27

    Arkansas State (3-2) at Troy (3-2), 4 p.m. ET
    Prediction: Troy 28, Arkansas State 20

    Connecticut (0-5) at Rice (3-2), 5 p.m. ET
    Prediction: Rice 26, UConn 14

    Tulsa (3-2) at Florida Atlantic (1-3), 6 p.m. ET
    Prediction: Tulsa 34, FAU 27

    Colorado (3-2) at Arizona State (1-4), 6:30 p.m. ET
    Prediction: Colorado 38, Arizona State 24

    South Alabama (2-3) at Louisiana-Monroe (2-2), 7 p.m. ET
    Prediction: South Alabama 27, ULM 17

    Old Dominion (2-3) at Southern Miss (1-4), 7 p.m. ET
    Prediction: Southern Miss 31, Old Dominion 28

    Texas Tech (2-3) at Baylor (2-3), 8 p.m. ET
    Prediction: Texas Tech 35, Baylor 31

    TCU (3-2) at Iowa State (2-3), 8 p.m. ET
    Prediction: TCU 34, Iowa State 17

    Colorado State (2-2) at Utah State (2-3), 8 p.m. ET
    Prediction: Utah State 31, Colorado State 27

    San Jose State (1-4) at Boise State (2-3), 8 p.m. ET
    Prediction: Boise State 36, San Jose State 28


    Gambling problem? Call (877-8-HOPENY) or text HOPENY (467369).

    If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL/IN/MI/NJ/PA/WV/WY), 1-800-NEXT STEP (AZ), 1-800-522-4700 (CO/NH), 888-789-7777/visiting ccpg.org/chat (CT), 1-800-BETS OFF (IA), 1-877-770-STOP (7867) (LA), visiting OPGR.org (OR), or calling/texting TN REDLINE 1-800-889-9789 (TN) or 1-888-532-3500 (VA).

    Odds and lines subject to change. 21+ (18+ NH/WY). AZ/CO/CT/IL/IN/IA/LA/MI/NH/NJ/NY/OR/PA/TN/VA/WV/WY only. Eligibility restrictions apply. See draftkings.com/sportsbook for full terms and conditions.

X