Super Bowl 2024: Initial Odds, Final-Score Prediction for 49ers vs. Chiefs

The matchup for Super Bowl LVIII is set, as the Kansas City Chiefs defeated the Baltimore Ravens in the AFC Championship Game and the San Francisco 49ers beat the Detroit Lions in the NFC Championship Game to advance Sunday.

The 49ers were the top seed in the NFC and looked like one of the top teams in the league this season, and now they'll get the chance to become champions. Their path to the Super Bowl wasn't an easy one. San Francisco survived the divisional round against the Green Bay Packers before erasing a 17-point deficit against the Lions to win the NFC championship.

The Chiefs, who were the No. 3 seed in the AFC, had to get through a pair of road tests on their way to a fourth Super Bowl in five years. After beating the Miami Dolphins in a frigid Arrowhead Stadium, Kansas City got past the Buffalo Bills on the road before winning in Baltimore.

Odds (via DraftKings Sportsbook)

Spread: 49ers (-2)

Moneyline: Niners (-125), Chiefs (+105)

Over/under: 47.5

Date: Sunday, Feb. 11, 6:30 p.m. ET

Location: Allegiant Stadium, Las Vegas, Nevada

The game between the Chiefs and 49ers will be a rematch of Super Bowl LIV, when Kansas City won 31-20.

Kansas City came into Sunday's AFC Championship Game as an underdog, but Mahomes said the Chiefs "never feel like underdogs." As far as the odds are concerned, though, they will be underdogs once again against the 49ers in the Super Bowl.

Compared to the last three Chiefs teams that reached the Super Bowl, this one didn't dominate throughout the regular season and faced plenty of doubt heading into the postseason. Kansas City proved this year, however, that any team coached by Andy Reid and led by Mahomes has a fighting chance.

San Francisco came into the season hungry for a Super Bowl, and the 49ers have looked like one of the top teams in football all year. Led by star running back Christian McCaffrey and promising quarterback Brock Purdy, the 49ers certainly have what it takes to keep up with Kansas City's electric offense.

With a powerful offense and a more than capable defense, the 49ers will look to avenge the Super Bowl loss from 2019.

However, with the way Mahomes has played this postseason, the Chiefs will be tough to beat.

Prediction: Chiefs 27, 49ers 21